Several other races remain too close to call, including in Maine, where Senator Susan Collins leads the Democratic nominee, Sara Gideon. In a special Senate election in Georgia, the incumbent Kelly Loeffler is headed to a January runoff against the Democrat Raphael Warnock. Democrats’ struggled to match their 2016 margins among Hispanic voters. We’ve covered that theme in some detail in this newsletter, and it hurt Biden, especially in Florida and Texas. If Biden holds onto his lead in Nevada and Wisconsin, he would need to win only one of three states — Georgia, Michigan or Pennsylvania — to secure a majority of electoral votes (and could still lose North Carolina). “The vote-counting happening now is…. exactly what we knew and reported would happen. This is legitimate vote-counting, of ballots that were returned before or on Election Day.” — Scott Detrow, NPR Make something comfortingCornbread tamale pie, a recipe from The Joy of Cooking, is a crowd-pleasing classic. It elevates a beef chili by baking it with a simple cornbread batter on top.DiversionsGames Democratic Senate candidates were running slightly behind Biden in several states, making it difficult for the party to retake Senate control. The outstanding ballots are mostly mail-in ballots, which are likely to favor Biden, because more Democrats than Republicans voted early this year. He leads in the current vote count in Nevada and Wisconsin, while Trump leads in the remaining four. “I don’t think people have fully internalized how Democratic these mail and absentee ballots will be in MI/PA/WI,” Nate wrote. Joe Biden is now the favorite to win the presidency, and Republicans are favored to keep Senate control — but both results are far from certain. And Democrats failed to win the resounding victory that pre-election polls had suggested they could.- Advertisement – Many of the state polls were wrong and underestimated support for Republicans — again. A big question in coming days will be why: Did polls again fail to include enough working-class white voters, as was the case in 2016? Or was it something else? Democrats needed to win at least five of the 14 competitive Senate races and have so far won only two. Six races remain up in the air. The only incumbent Republicans to have lost are Martha McSally in Arizona and Cory Gardner in Colorado. Even with Biden’s seeming advantages at this point, the country has never experienced an election with such heavy voting by mail, which creates significant uncertainty. It is entirely possible that Trump will retain his lead in the states where he now leads and win the election. The pangram from yesterday’s Spelling Bee was chantey. Today’s puzzle is above — or you can play online if you have a Games subscription. In Iowa, Senator Joni Ernst, a Republican, won re-election. Republicans also won races in Montana, South Carolina — where Lindsey Graham held on to his seat — and Texas. “Biden’s the favorite, even if narrowly, just about everywhere,” Nate Cohn of The Times tweeted, listing five of the six states above (all but North Carolina). Sean Trende of RealClearPolitics agreed: “Would probably rather be Biden than Trump.” The situation in the Senate is different — and more favorable to Republicans. They appear to be in a strong position to retain Senate control, which would give them a veto over nearly all of a President Biden’s legislative plans. Biden, addressing supporters after midnight, urged patience. “We believe we’re on track to win this election,” he said. “We’re going to have to be patient until the hard work of tallying the votes is finished. And it ain’t over until every vote is counted, every ballot is counted.” Subscribers make our reporting possible, so we can help you make sense of the moment. If you’re not a subscriber, please consider becoming one today.PLAY, WATCH, EAT, BAKE You can visit The Times all day for the latest coverage. Want to get The Morning by email? Here’s the sign-up.Good morning. There is no presidential winner yet. Biden appears to be in a better position than Trump, and Republicans seem in better shape to hold Senate control. The outcome is unclear in six swing states — Georgia, Michigan, Nevada, North Carolina, Pennsylvania and Wisconsin — and all are still counting votes. We may get some final vote counts today, while others could take a few days. “This is an extremely flammable situation and the president just threw a match into it,” Chris Wallace said on Fox News, after Trump’s remarks. “He hasn’t won these states.”“Donald Trump called it a ‘fraud’ to continue to count votes. This does not sound like a democracy.” — Olivia Nuzzi, New York Magazine“What Trump did tonight is shocking, even though he’s been telegraphing this for some time. He’s primed his supporters to believe any result that doesn’t involve him winning is fraud.” — Rosie Gray, BuzzFeed News“Trump may indeed win. But he certainly hasn’t yet. And, he doesn’t get to say that your vote shouldn’t be counted.” — S.E. Cupp, CNN“Every single serious analysis I read of this election said that it would be long and drawn out, and that Trump would try to steal the election by trying to discount late-arriving Biden votes. And now that it’s happening…everyone seems shocked.” — Anne Applebaum, The Atlantic “Incredible how competitive Trump is with 230K+ covid deaths and kids being locked in cages and everything else. Even if Biden wins he will have to govern in a Trump country. This is who America is.” — Gabriel Sherman, Vanity Fair“In any normal presidential democracy, this would not be a close election right now. It is only close because of our strange Electoral College.” — Lee Drutman, New America think tank“A key question moving forward is whether public opinion polling is irreparably broken or if polling is just broken in elections with Trump on the ballot.” — Nathan Gonzales of Inside Elections.“Biden POTUS with GOP Senate is a recipe for a horrifically nasty politics next year.” — Matt Glassman, Georgetown political scientist“Democrats had hoped for a massive, unequivocal repudiation of Donald Trump for his mishandling of the pandemic, his raging White House incompetence, and his disdain for the rule of law. Instead, there was the sobering message that Trump’s support in key states like Florida was, in truth, greater than the polls had predicted.” — Walter Shapiro of The New Republic.The Senate Democrats flipped two seats: John Hickenlooper defeated Gardner in Colorado, and Mark Kelly defeated McSally in Arizona. Further down, you’ll find information on some of this year’s other races — including more detail on the Senate, as well as the latest on state ballot initiatives. First, though, I want to give you a selection of commentary on the national scene.Election Commentary Republicans flipped one seat: Tommy Tuberville beat the Democrat Doug Jones in Alabama. Gary Peters, the Democratic incumbent in Michigan, is locked in a close race with his Republican challenger, John James; it will depend on the outstanding votes. – Advertisement – Trump falsely declared himself the winner around 2:30 a.m. Eastern. He said he would call on the Supreme Court to stop counting ballots in states where he led, while urging more counting in states where he was behind. He claimed “fraud” (for which there is no evidence) and he called the election an “embarrassment to the country.” – Advertisement – Here’s where we stand after a topsy-turvy election night, in which the situation shifted multiple times: The counting of ballots seems likely to be slowest in Michigan and Pennsylvania. Officials in Pennsylvania have said they expect all votes to be counted by Friday. – Advertisement –
Robbie Power set a steady pace as he attempted to make all the running in the Racing TV HD On sky 426 Beginners’ Chase over two miles and three furlongs and he put in a good round of jumping.Market rival Sporting John was expected to be the big danger, but he was a big disappointment and was out of contention from the third-last fence.It was left to the Fergal O’Brien-trained Silver Hallmark to put it up to Fiddleronthehoof (11-10) and he took a narrow lead two out. There was nothing between the pair at the last, but Colin Tizzard’s charge found extra on the run-in to score by a head.- Advertisement – “He put his Ffos Las experience to good use,” said Tizzard.“He’s a good, solid horse. I think we’ll see him over three miles before too long, but he got the job done.“It’s just nice to see. Whether he needs to go up (in trip) now, I don’t know.- Advertisement – Fiddlerontheroof put up an ultra-game display to open his account over fences at Exeter.Winner of the Grade One Tolworth Novices’ Hurdle in January, Fiddlerontheroof had been beaten on his chasing debut by If The Cap Fits at Ffos Las last month, but he learnt plenty from that experience.- Advertisement – – Advertisement – “The ground is only just good at the moment. In the winter we do know he handles the heavy as well. He’s a strong horse so it’s good going forward.”He added: “They need to have three or four weeks off. We don’t want to empty him out before Cheltenham, but there are good races coming up before then.“I suppose we’ll be looking at the one around Kempton (Kauto Star Novices’ Chase). That’s only a month on.“It’s just nice to see him win and we can sit down and think about it in a day or two.”Fiddlerontheroof is 25-1 for the Marsh Novices’ Chase at the Cheltenham Festival with Betway and was cut to that price from 33-1 with Paddy Power. Coral gave him a quotes of 20-1 for the Marsh and also the RSA Chase.Tizzard and Power were completing a double after the win by Ofalltheginjoints (85-40 favourite) in the limited handicap chase.
– Advertisement – – Advertisement – Katie Taylor, Terri Harper and Rachel Ball are in world title fights at Wembley Arena; historic triple-header is on Saturday, live on Sky Sports, and also streamed free on YouTube, Facebook and skysports.com Last Updated: 13/11/20 3:59pm – Advertisement –
On both sides of the border were trying to close the gaps, he said. But determining how much risk those gaps in rules represent and what to do about tricky problems such as handling SRM disposal is still hotly debated, he said. The FDA had also previously banned high-risk cattle tissues, or “specified risk materials” (SRMs), from human food, food supplements, and cosmetics. SRMstissues most likely to harbor the BSE agent in an infected animalinclude the brain, skull, eyes, spinal cord, vertebral column, and certain nerve bundles in cattle 30 months or older, plus the tonsils and small intestine of all cattle. Officials reiterated that message recently in response to a new round of questions raised by media reports over tracing of animal feed suspected of containing materials from the BSE-infected cow found in Canada last year. “FDA recommends that any such adulterated feed or feed ingredients be recalled or otherwise removed from the marketplace,” the guideline says. The FDA recommendation is not binding, and the agency said it would continue to accept comments on it. Cattle can contract the prion disease BSE, one of several transmissible spongiform encephalopathies, by eating feed containing material from infected cattle. To prevent this, in 1997 the FDA banned the use of most mammalian protein in feed for ruminant animals. The rendering of cattle into feed for nonruminant animals such as pigs and chickens remains a common practice, but it has come under heightened scrutiny since the discovery of one cow with BSE in Canada and one in the United States in 2003. The concern is that contaminated material could be fed to cattle through cross-contamination in feed plants or if feed intended for other animals is given to cattle. The challenge becomes that there are lots of ways for the material to get back into cattle feed, Hueston said. See also: The latest recommendation is another government step to close gaps in BSE prevention, said Will Hueston, DVM, PhD, director of the University of Minnesota’s Center for Animal Health and Food Safety in St. Paul. Hueston was also part of an international review team (IRT) that assessed BSE cases in the United States and Canada. Sept 30 FDA guidance on use of material from BSE-positive cattle in animal feedhttp://www.fda.gov/OHRMS/DOCKETS/98fr/2004d-0438-gdl0001.pdf Canada and the United States may be close to taking what some view as a key step in that process: banning SRMs from all animal feed. FDA announced last July its intention to propose such a ban. Roughly 1,400 individuals and 100 industry groups sent letters during a subsequent comment period, Linda Grassie, the communications director for the FDA Center for Veterinary Medicine, said today. Testing backlogs led to the infected animal being rendered, Sergio Tolusso, feed program director for the Canadian Food Inspection Agency, told Meatingplace.com last week. Investigators traced the feed, visited 200 farms and found several cases where cattle encountered the feed, intended only for pigs and chickens. Three cattle farms were quarantined and 63 cattle destroyed, according to the Canadian Broadcasting Corporation. Hueston said that ideally, Canada and the United States would develop complementary response systems. Oct 15, 2004 (CIDRAP News) The US Food and Drug Administration (FDA) has announced a new guideline to prevent the use of cattle infected with bovine spongiform encephalopathy (BSE) in any animal feed. Though a proposal is expected, Grassie said she doesnt know when it will be issued. Canada is also expected to take its rules a step further soon. The Canadian government announced in July that it would ban the use of SRMs in animal feed. One reason for the delay in implementing the Canadian ban is the problem of determining how to safely dispose of those body parts, officials said. The use of most mammalian protein in cattle feed has been banned since 1997, but the Sep 30 recommendation, which took effect immediately, goes further. It says that animal feed and feed ingredients with material obtained from a BSE-positive animal are considered adulterated and cannot be fed to any other animals.
Aug 3, 2006 (CIDRAP News) – In an apparent policy shift, Indonesia promised today to freely share genetic data on H5N1 avian influenza viruses, according to a Bloomberg news report.That announcement comes 2 days after the United Nations Food and Agriculture Organization (FAO) and the World Organization for Animal Health (OIE) pledged to “systematically” publish avian flu virus sequences and urged others to follow suit.The two announcements raise the prospect of better tracking of mutations in the virus, which should help in the development of vaccines to use in case the H5N1 virus evolves into a strain capable of causing a human pandemic.Indonesia’s health minister, Siti Fadilah Supari, said the country will deposit avian flu virus data in GenBank, a public database of genetic sequences, according to today’s Bloomberg report. She said data from the recent family case cluster in Sumatra involving person-to-person transmission would be included.The journal Nature reported Jul 28 that until very recently, Indonesia had shared few, if any, H5N1 virus samples from birds over the past year. Peter Roeder, an FAO official in Indonesia, was quoted as saying the FAO had received no sequence data from poultry viruses from August 2005 until very recently, when 91 samples arrived at an OIE facility in Geelong, Australia.The Indonesian announcement was welcomed by the World Health Organization (WHO), according to Bloomberg. “We are very pleased with the Indonesian government decision. This will be important for the international response to avian influenza,” George Petersen, WHO representative in the country, told Bloomberg.The OIE and FAO announced Aug 1 that their joint network of expertise on avian influenza, called OFFLU, would “systematically make avian influenza virus sequences accessible to the entire scientific community,” according to an FAO news release. The groups promised to send virus samples to the US National Institutes of Health for sequencing and would deposit the sequence data in GenBank.”With this gesture OFFLU reiterates its call to the world’s scientists, international organizations and countries for a global sharing of virus strains and sequences,” the FAO said.Virus strains are often considered intellectual property, and some experts believe that sharing them can possibly hamper research progress and scientific publication, the FAO statement said.OFFLU was launched in April 2005 with the aim of sharing avian flu data and virus samples internally and with the wider scientific community, the FAO said. In February of this year, OFFLU launched a campaign for openness when Dr. Ilaria Capua of Italy, chair of the network’s Scientific Committee, published sequence data on H5N1 strains from Nigeria and Italy and urged 50 colleagues around the world to share their data.In March, the OFFLU Scientific Committee decided “to put new emphasis on the need for further collection, characterization, and exchange” of avian flu viruses and for expansion of sequence data, the FAO reported. At about the same time, Capua and four OFFLU colleagues wrote a letter to the journal Science promising to make H5N1 samples available for sequencing.See also:Aug 1 FAO news release about H5N1 data sharinghttp://www.fao.org/newsroom/en/news/2006/1000374/index.htmlAug 1 OIE news releasehttp://web.oie.int/eng/press/en_060801.htmOFFLU sitehttp://www.offlu.net/
Mar 31, 2008 (CIDRAP News) – Indonesia’s health ministry today announced fatal H5N1 avian influenza infections in two young people, aged 11 and 15, and said a 22-month-old girl is hospitalized with an H5N1 infection.If the World Health Organization (WHO) confirms the three cases, its human H5N1 count for Indonesia will reach 132 cases with 107 deaths.Nyoman Kandun, director general of communicable diseases for Indonesia’s health ministry, said one of the patients is a 15-year-old boy from Subang, West Java province, who died on Mar 26, according to a Reuters report today.The boy’s brother died recently, but Kandun told Reuters the deaths do not represent a family case cluster, because the brother died of dengue fever. No other details were available about the brother, such as whether health officials obtained and tested samples for the H5N1 virus.Kandun said the 11-year-old girl died Mar 28 and was from Bekasi, east of Jakarta, according to the Reuters report. Some media outlets are reporting the girl’s age as 12.Kandun said dead chickens were found in the boy’s neighborhood, but officials weren’t sure if the girl had been exposed to sick or dead birds, Reuters reported.The health ministry said today that a 22-month-old girl from Bukit Tinggi in West Sumatra has tested positive for an H5N1 infection, according to Reuters.She was transferred to a bird flu specialty hospital on Mar 24 after she experienced a high fever and other suspicious symptoms, Agence France-Presse reported today.Lily Sulistyowati, spokeswoman for Indonesia’s health ministry, told Reuters the girl got sick on Mar 19 and is receiving treatment at a hospital in Padang, where her condition is improving.Animal-health authorities are checking the girl’s neighborhood to determine if she could have been exposed to infected backyard poultry, Reuters reported.Indonesia leads the world in H5N1 cases and deaths. WHO confirmation of the latest illnesses will raise the global H5N1 total to 376 cases with 238 deaths.
Oct 28, 2008 (CIDRAP News) – A fifth case has been confirmed in the recent outbreak of febrile illnesses caused by a mysterious virus in South Africa, and preliminary tests have supported earlier suspicions that it is new member of the arenavirus family, South African health officials announced recently. Another nurse, who helped take care of the paramedic, also got sick but has so far survived. Melinda Pelser, a spokeswoman for Morningside Medi-Clinic in Johannesburg, where the nurse works and is being treated, said she was in serious condition but “on the road to recovery,” according to the Independent Online report. In the fatal cases, the illness lasted 9 to 12 days, culminating in sudden deterioration with respiratory distress, neurologic signs, and circulatory collapse. The agency said there were no more suspected cases in the outbreak. The number of people being monitored because of possible exposure to the patients has dropped from 94 to 31, according to the Independent Online. The NICD said tests by its own laboratory and the US Centers for Disease Control and Prevention (CDC) have confirmed an Old World arenavirus in all five cases. An analysis of genetic sequence data generated by the NICD, the CDC, and Columbia University in New York City “appears to indicate that the current outbreak is caused by a unique Old World arenavirus,” the NICD statement said. The illness worsened in the course of a week, with all four patients suffering diarrhea, sore throat, and a rash on the face and throat. Three patients also had facial swelling. The cleaner, a woman named Maria Mokubong, died Oct 6, according to a report today by the Independent Online, a South African news service. “Bleeding was not a prominent feature,” but one patient had a petechial rash, and another had oozing of blood from venipuncture sites. Oct 13 CIDRAP News story “Tests indicate an arenavirus in South African deaths” The hospital cleaner who died of the infection was bleeding and confused when she presented for treatment, and she died soon afterward, the NICD said. The agency gave the following clinical profile for the other patients: Arenaviruses are carried by rodents and secreted in their urine. Recognized “Old World” arenaviruses include lymphocytic choriomeningitis virus (which actually occurs worldwide) and Lassa fever virus, which affects as many as 500,000 people annually in West Africa, the NICD said. Several arenaviruses found in South America, including Junin, Machupo, Sabia, and Guanarito viruses, cause a hemorrhagic fever syndrome, the statement noted. A worker who fell ill and died after cleaning a hospital room where the first case-patient in the outbreak had stayed was confirmed to have the virus, South Africa’s National Institute for Communicable Diseases (NICD) said in an Oct 24 update. Three other people had died of the virus earlier. The first was a Zambian woman who fell ill during a safari in South Africa. Subsequently a paramedic who helped care for the Zambian woman during her transfer to a Johannesburg hospital and a nurse who cared for the same patient during her hospitalization succumbed to the virus. CIDRAP overview of viral hemorrhagic fevershttp://www.cidrap.umn.edu/cidrap/content/bt/vhf/biofacts/index.html All initially presented with an influenza-like illness including fever, headache, and muscle aches. See also: “Preliminary testing indicates that the virus associated with the present nosocomial outbreak is a distinct new member of the family,” the NICD added.
Apr 20, 2009Canada set to shuffle antiviral stockpileCanada will adjust the combination of antiviral medications in its national emergency stockpile because of concern about ostelamivir (Tamiflu) resistance among influenza viruses, the Canadian Press (CP) reported today. The Public Health Agency of Canada said it will boost its supply of zanamivir (Relenza), along with older antiviral medications such as amantadine and rimantadine. Canada’s emergency stockpile, a backup to the country’s national antiviral stockpile, currently contains 14 million doses, enough to treat 1.4 million people. Arlene King, a federal pandemic planning official, told the CP that discussions are under way with provincial and local officials to also adjust the mix of medications in the national antiviral stockpile, which holds most of the country’s pandemic flu drugs—55.7 million doses, enough to treat about 5.6 million people.[Apr 20 CP story] H5N1 hits Tibetan poultry farmAgriculture officials in China reported yesterday that the H5N1 avian influenza virus struck a farm near Lhasa, the capital of Tibet, according to a report from the World Organization for Animal Health (OIE). The report said the birds were chickens from a live bird market. The outbreak killed 1,500 of the farm’s 3,179 poultry, and the remaining birds were culled to prevent the spread of the disease. Tibet’s last outbreak was reported in April 2008, according to previous reports.[Apr 10 OIE report]Study: Intranasal flu vaccine topped injected vaccine in military recruitsIn a study involving thousands of US military personnel, the live attenuated influenza vaccine (LAIV, or FluMist) provided better protection in new recruits than a conventional trivalent injected vaccine (TIV) did, according to a new report published by Vaccine. In 2005-06 and 2006-07, rates of influenza-like illness (ILI) were 22% to 51% and 18% to 47% lower in the LAIV group than in the TIV group. Seasoned service personnel, however, had slightly but significantly greater protection with TIV than with LAIV, according to the report by military medical researchers. They also found that ILI rates were much higher in the recruits than in seasoned soldiers.NIAID grant supports new biodefense centerOregon Health and Science University (OHSU) and the University of Washington recently announced that they have received a 5-year, $40.7 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) to establish a regional biodefense and emerging infectious disease center, according to an Apr 15 press release from OHSU. The Pacific Northwest Regional Center for Excellence for Biodefense and Emerging Infectious Diseases is based at OHSU and involves several other partner institutions. Researchers will investigate a broad range of diseases and pathogens, including Ebola, SARS, avian and 1918 influenza, dengue fever, yellow fever, and West Nile virus. The center’s research will focus on two main areas in its search for new therapeutic targets: defects in the aging immune system and the identification of disease-host interactions through genomics and genetic analyses.Foodborne disease cases in Toronto estimated at 437,000 per yearA new report from Toronto Public Health (TPH) estimates the city’s burden of foodborne disease at 437,093 cases per year, or about one case for every six residents. The cost of foodborne illness in the city is estimated at $476 million to $587 million a year. Outbreak-associated disease cases are highest in the winter, whereas sporadic cases are most common in the summer and early fall, the report says. It says sporadic cases have declined in the past 5 years, following the introduction of TPH’s DineSafe program. TPH posts restaurant inspection results online and on signs in restaurant windows.[TPH report] Initial probe finds no infectious disease in horses’ deathsIn an investigation into the deaths of 21 horses at the site of a Wellington, Fla., polo match, no evidence has been found so far to suggest an infectious disease cause, Charles Bronson, Florida’s Agriculture and Consumer Services (FACS) commissioner, said today in a press release. The horses were on a Venezuelan team that was scheduled to play yesterday. They didn’t show any signs of illness in the morning, but after they were transported to the polo stadium, some animals were found dead and others had severe illness signs, including depression, breathing difficulties, and problems moving and standing, according to the release. Fourteen horses died by yesterday evening and the other seven died overnight. No other horses appear to have symptoms. State officials said the rapid onset of sickness and death suggests an adverse drug reaction or toxicity. Authorities are conducting necropsies and toxicology tests, but results may not be known for several days.
FlixBus, the European leader in passenger transport, is expanding its network of international bus lines from Croatia at the beginning of the new season. Zagreb is thus additionally connected with new destinations in Switzerland and Germany by daily direct lines.Thanks to the constant investment in the development of the FlixBus green network from 22.3. passengers will be able to travel daily on the route Zagreb – Ljubljana – St. Gallen – Zurich – Basel – Freiburg stand out from FlixBus. “Listening to the wishes of passengers, and monitoring passenger traffic in Croatia, we noticed that this route has long been in great demand for a simple and affordable connection. With this night line, we have expanded our offer and provided passengers with new destinations in Switzerland and Germany for the recent spring trips. Offering an alternative to air and rail transport with shorter journeys and affordable prices, our goal is to connect Croatian cities with as many destinations in Europe as possible and make Flixbus quality and standard available to everyone..” said Petra Milanović, Public Relations Manager for FlixBus CEE South region.By digitizing the bus industry, FlixBus has made it possible to connect cities across EuropeIn just four years, Flixbus has managed to create a network of bus lines in 26 European countries that connects 1400 destinations with over 250.000 daily connections. The business model that combines the traditional bus industry and high technology allows passengers to travel cheaply and comfortably in state-of-the-art green buses. “Our Croatian bus partners have recognized this successful business model, which has been accepted by passengers throughout Croatia. Currently, more than 100 destinations in Croatia are connected to the FlixBus network by direct connections with 10 European countries, and further development and better frequency are planned.”Concluded Milanovic.FlixBus buses offer free Wi-Fi, sockets next to the seats, more space between the seats, free luggage and the possibility of changing and canceling reservations up to 15 minutes before departure, online ticket purchase without waiting in lines at the box office and passenger identification only via QR code and smart phone.